The IGF-1 Activator
- Only known compound to increase your body’s own IGF-1 in human cells
- Supports cartilage regeneration, joint repair & bone density
- Enhances muscle protein synthesis and healthy aging
- Backed by NIH-funded research
Why PhytoZon?
CLINICALLY-STUDIED JOINT SUPPORT
PhytoZon features research-backed ingredients shown to support joint comfort and mobility. In clinical trials, 94% of participants experienced improved flexibility within 30 days.
ADVANCED CELLULAR REPAIR
Features patented RNI249® from Maca, supported by NIH research, to naturally boost production for enhanced cellular repair and recovery.
TARGETED INFLAMMATORY BALANCE
Contains Vincaria® (alkaloid-free Cat's Claw), clinically shown to help maintain healthy inflammatory response in joints and throughout the body.
NATURAL IGF-1 ACTIVATION
RNI249® is the only natural substance shown to increase your body's own healing supporting cellular repair and tissue regeneration for healthy aging.
COMPREHENSIVE MOBILITY SUPPORT
supports muscle function, bone strength, and tissue repair - key factors for maintaining daily movement, flexibility, and an active lifestyle.
REAL-WORLD RESULTS
Customers report improved morning mobility, enhanced daily comfort, better flexibility, and renewed confidence in their active lifestyle!
CLINICALLY-STUDIED JOINT SUPPORT
PhytoZon features research-backed ingredients shown to support joint comfort and mobility. In clinical trials, 94% of participants experienced improved flexibility within 30 days.
ADVANCED CELLULAR REPAIR
Features patented RNI249® from Maca, supported by NIH research, to naturally boost production for enhanced cellular repair and recovery.
TARGETED INFLAMMATORY BALANCE
Contains Vincaria® (alkaloid-free Cat's Claw), clinically shown to help maintain healthy inflammatory response in joints and throughout the body.
NATURAL IGF-1 ACTIVATION
RNI249® is the only natural substance shown to increase your body's own healing supporting cellular repair and tissue regeneration for healthy aging.
COMPREHENSIVE MOBILITY SUPPORT
supports muscle function, bone strength, and tissue repair - key factors for maintaining daily movement, flexibility, and an active lifestyle.
REAL-WORLD RESULTS
Customers report improved morning mobility, enhanced daily comfort, better flexibility, and renewed confidence in their active lifestyle!
What If Your Body Could Rebuild Cartilage Like It Did at Age 20?
The IGF-1 Revolution: Your Body's Repair Blueprint
What is IGF-1?
Rebuilding cartilage and bone
Repairing muscle and nerve tissue
Enhancing immunity and insulin sensitivity
At age 20, IGF-1 peaks—fast healing, strong body, sharp mind.
By 40, levels drop up to 50%. By 60, they’re down 80%.
This decline, known as somatopause, is behind many signs of aging—muscle loss, joint pain, wrinkles, and slower recovery. So, what if you could turn back that clock?
RNI249®: The Only Substance That Increases Your Body's Own IGF-1
Backed by the National Institutes of Health
RNI249® is a patented, highly concentrated extract from Lepidium meyenii (Maca), a radish-like tuber found only on the inner slopes of the Andean Mountains.
Research sponsored by two divisions of the NIH — the National Institute on Aging and the National Institute of Arthritis and Musculoskeletal Disease — revealed a world-first discovery:
RNI249® naturally increases your body’s own IGF-1 production at the cellular level.
Published by Case Western Reserve University
In controlled human cell studies, RNI249® was shown to significantly increase IGF-1 production within cells — a key factor in repair, recovery, and regeneration.
NIH-Sponsored Clinical Trial – Osteoarthritis Patients
In a 30-day study, the results were remarkable:
- 94% experienced statistically significant improvement in mobility and flexibility
- Most improved within 7 days
- Marked reduction in pain compared to glucosamine (the positive control)
- Dramatic overall results confirmed within the trial period
Breakthrough Science 🔬
Proven Research 📚
Clinical Results 🏆
The Complete PhytoZon® Formula
Advanced Nutrients for Cellular Repair & Healthy Aging
RNI249®
Vincaria®
Progrado® & Zangrado®
Lutein
Lycopene
Piperine
The Inflammation Regulator
Clinically validated to:
- Regulate TNF-Alpha, the master switch behind 35+ inflammatory pathways
- Modulate NF-κB, controlling inflammation at the genetic level
- Protect the GI tract from NSAID-related damage
Clinical Results:
- 90% experienced relief
- Most improved in <5 days
- Effective at a single 100mg daily dose
- Combined with RNI249®: highly effective for knee osteoarthritis
University Research:
LSU & Albany Medical College found that removing alkaloids makes Vincaria® more targeted and more powerful—without pharmaceutical side effects.
Sensory Neuron & Cartilage Regulators
Progrado®
- Regulates MMPs—the enzymes that break down cartilage
- Boosts cellular IGF-1
- Helps repair cartilage faster than it degrades
- Provides cardiovascular-supportive proanthocyanidins
- Supports nausea, ulcers, IBS & GERD
Zangrado®
- Reduces pain, itching & sensory nerve overstimulation
- Effective for bites, dermatitis & skin healing
- Internal support for nausea, diarrhea & respiratory irritation
The Result:
Your body finally repairs itself faster than it breaks down.
Vision Protection & Antioxidant Support
- Filters blue light & protects the retina
- Supports visual acuity, contrast & night vision
- Reduces risk of AMD, glaucoma & cataracts
- Provides whole-body antioxidant and skin benefits
Heart & Prostate Support
- Supports healthy blood pressure & heart function
- Reduces LDL oxidation & improves HDL levels
- Supports prostate health & healthy PSA
- Helps reduce atherosclerosis risk
- Contains potent anti-inflammatory properties
Mediterranean Advantage:
Higher lycopene intake is linked to longevity and improved quality of life.
2,000% Bioavailability Enhancer
Boosts absorption of:
- Curcumin (up to 2,000%)
- Essential vitamins (A, B-complex, C, E)
- Minerals (iron, zinc, calcium, selenium, magnesium)
- Herbal compounds (resveratrol, CoQ10, green tea extract)
- All essential amino acids
PhytoZon® vs. Standard Joint Supplements
Increases your body's own IGF-1 production
Provides building blocks only
Regulates inflammation at the genetic level
No effect on inflammation
Protects existing cartilage from breakdown
Minimal clinical evidence for cartilage regrowth
No GI damage—actually protects stomach lining
GI damage (ulcers, bleeding)
Comprehensive formula addresses multiple pathways
Mask pain, doesn't heal
Published clinical trials with 94% success rate in participants with osteoarthritis
Too many health risks
Real People, Real Results
Your Questions Answered
How long before I notice results?
Most people notice initial improvements within 2-4 weeks (reduced discomfort, better mobility). Significant cartilage regeneration typically takes 3-6 months of consistent use. Remember, your body took years to degrade—healing takes time but it's real healing, not just masking symptoms.
Can this really regrow cartilage in bone-on-bone joints?
Published research shows RNI249® increases IGF-1 production, which stimulates chondrocytes to produce new cartilage. Many users (and their X-rays) report cartilage regrowth even in severe cases. However, individual results vary based on severity and overall health.
Is this safe to take with other medications?
PhytoZon® contains natural plant extracts. However, Vincaria® affects inflammation pathways, so consult your healthcare provider if you're on blood thinners or immunosuppressants. Piperine can increase absorption of some medications, so discuss with your doctor.
I have chronic widespread discomfort and inflammation. Can this help?
PhytoZon® supports the body's natural inflammatory response through multiple pathways (Vincaria® regulates inflammation, Progrado®/Zangrado® support sensory neuron function, RNI249® promotes cellular repair). Many users with various types of chronic discomfort report improvements. However, for specific health concerns, always work with your healthcare provider to develop a comprehensive plan.
Can I take this if I'm waiting for joint replacement surgery?
Absolutely. Many people have avoided surgery entirely by regenerating enough cartilage to restore function. At minimum, you'll be in better condition going into surgery. Consult your orthopedic surgeon.
Why haven't I heard about this before?
RNI249® is a patented ingredient with published research, but it's not widely known because it's not a pharmaceutical drug (no massive marketing budget). The science is solid—it's just not mainstream yet.
Will this help my vision too?
Yes! The lutein in PhytoZon® is clinically proven to improve visual acuity, protect against macular degeneration, and support overall eye health. It's a bonus benefit beyond the joint support.